In this episode, Rafael Neiman, M.D., of Orthopedic Trauma Surgeons of Northern California, discusses how he injected a 49-year-old female patient’s own bone marrow stem cells into the fracture and nonunion sites of both her legs that had not healed since injured in a skiing accident seven months earlier.  Dr. Neiman reports that complete fracture closure and union was achieved in both legs.  This case is noteworthy because Dr. Neiman treated his patient without open surgery by collecting, processing, and returning the patient’s own bone marrow stem cells at the patient’s bedside in the same procedure.  It has been widely reported in the scientific literature that percutaneous delivery of a high concentration of adult stem cells can enhance the rate and amount of bone formation.  Several studies have documented the effects of injected bone marrow cell concentrates in cardiovascular and orthopedic disease.  Until now, it has been difficult to process and concentrate adult stem cells from a patient’s own bone marrow at the point of care.