Smallpox vaccination started in the early 19th century. It was over a hundred years before another vaccine was introduced for widespread use. This was diphtheria toxoid, that was used nationally from 1940. The dates of the introductions of the different vaccines into the routine UK childhood immunisation schedule are shown in the table below.
Disease Routine vaccination started Routine vaccination stopped
Smallpox Early 1800s 1971
Diphtheria 1941
Tuberculosis (TB) 1953 2005
Polio 1956
Pertussis (whooping cough) 1958
Tetanus 1961 (in new 3 in 1 DTP)
Measles 1968
Rubella (German measles) 1971 (for teenage girls only)
MMR 1988
Hib (Haemophilus Influenzae) 1992
MMR 1996 (2nd MMR at 4 years)
Men C (Meningitis C) 1999
Pneumococcus 2006
The increasing vaccine burden
The number of vaccines routinely given to every child in the UK over the last hundred years is shown graphically below.