The Blakely Lab

 
 

My laboratory explores the molecular basis for neurotransmitter transporter structure, function and regulation. We use chimera, site-directed mutagenesis and site-specific chemical modification strategies to explore the topology and quaternary structure of biogenic amine transporters. We are evaluating what molecules control the proper localization and activity of transporter proteins using genetic (C.elegans), and molecular biologic methods. We are also evaluating whether human transporter polymorphisms impact the biosynthesis, trafficking and function of transporters and confer increased risk for autonomic, neurologic and mental disorders.

 

Randy Blakely, Ph.D.

Allan D. Bass Professor of Pharmacology and Psychiatry

Director, Silvio O. Conte Center for Neuroscience Research;

Vanderbilt Postdoctoral Training Program in Neurogenomics

email: randy.blakely@vanderbilt.edu

Curriculum Vitae:  Blakely CV(long) 4.04.12.pdf (651 kb)

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