DNA Based Self Assembly & Replication
Members: Balaji Kannan
Overview
This research focuses on utilisation of DNA as a sort of glue to assemble nanoparticles into definite nanoscale patterns. By using lithographically defined nanoscale patterns that are modified with single stranded DNA and throwing in gold nanoparticles modified with complementary DNA in solution, one can first “replicate” the pattern. Now, staggered DNA that’s complementary at both ends to the DNA on the nanoparticles can be put in solution to connect up the nanoparticles. Finally, if the DNA strands are all designed correctly, one can release these self-assembled nanoparticles that have a specific shape and size, without dismantling the whole structure, by heating. The whole process can be repeated a number of times to replicate the “master” pattern.