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Nano Engineering Lab
Last updated: Apr. 15, 2008
Arun Majumdar's 
Lecture on 
Global Energy
Artificial ‘Nose’ Scouts for Bombs
J. W. Jaworski, D. Raorane, J. H. Huh, A. Majumdar,and S. Lee published in Langmuir on 
‘Evolutionary Screening of Biomimetic Coatings for Selective Detection of Explosives’
[Link to Langmuir] [Press releases: LBNL, Discovery Channel] http://pubs.acs.org/cgi-bin/abstract.cgi/langd5/asap/abs/la7035289.htmlhttp://www.lbl.gov/today/2008/Apr/03-Thu/04-03-08.htmlhttp://dsc.discovery.com/news/2008/04/01/nose-smell-bomb.htmlhttp://livepage.apple.com/shapeimage_3_link_0shapeimage_3_link_1shapeimage_3_link_2
Left: Co-authors of the paper, from left to right: Prof. S.W. Lee, J.H. Huh, J.W. Jaworski, D. Raorane, Prof. A. Majumdar
 
Below:  Schematic illustration of the selective polymeric coating for the detection of explosive chemicals.  A DNT binding peptide as well as a TNT binding peptide were identified through the evolutionary screening process of phage display.  These highly selective receptors were conjugated with hygroscopic poly (ethylene glycol) linkers to provide attachment to chemical sensor surfaces to enhance the sensors selectivity.  Using such selective coatings, sensors may overcome there current limitations of non-specific binding thereby reducing the incidence of false alarms.