Serum Biomarkers of Prostate Cancer
Saturday, September 1, 2007
One of the problems of having a PSA that is elevated but less than 10 mg/ml is the probability of detecting prostate cancer. After we have determined you have an elevated PSA, usually a prostate biopsy is recommended. In those men with a PSA less than 10, there is a 1 in 6 chance that prostate
Imaging in Advanced Prostate Cancer
Sunday, July 8, 2007
Recently reported data from the National Cancer Institute Surveillance, Epidemiology, and End Results Program (SEER) demonstrate that approximately 90% of patients, regardless of race, were diagnosed with localized prostate cancer between 1995 and 2000. Currently, in the Las Vegas area, I have
Clinically Insignificant Cancer
Sunday, April 15, 2007
Clinically insignificant cancer is a indolent, slow growing disease in many patients and may not pose a threat during a patient’s lifetime.
The challenge is to identify those patients who are not likely to experience significant progression.
These are some of the parameters I consider in the
Prostate Biopsy
Sunday, April 15, 2007
The prostate biopsy is the standard of care for the initial diagnosis of prostate cancer. This pertains to men with significant PSA changes and/or suspicious digital rectal examination. However, up to 30% of the performed transrectal ultrasound guided biopsies are negative despite a persistent
Cryosurgical Ablation of the Prostate
Tuesday, April 3, 2007
I have been using cryotherapy of the prostate more in my practice. For the patient population that is suited for this therapy it is a great option. We are achieving great continence rates and moderate success on potency rates. Although it is too early to tell, if this trend continues I should meet
PCA3
Monday, April 2, 2007
PCA3 is a new prostate-specific gene that is highly over-expressed in prostate cancer. Specifically it is a nucleic acid amplification assay detecting in the urine the expression of PSA RNA as a marker of prostate cells and PCA3 RNA which is selectively expressed in the majority of prostate
Prostate Cancer Screening
Monday, April 2, 2007
Screening for Prostate Cancer
How do you effectively screen for the most common cancer in American men and keep costs reasonable? Also, realize that many men will get prostate cancer (~16%) but few will die from the disease.
In general, most urologists recommend screening if life expectancy is
Prostate Cancer Health
Friday, March 30, 2007
I have been thinking of changing around some of my recommendations I give to my patients regarding prostate cancer prevention.
There are 4 groups of patients that I am concerned with.
1. Patients with a rising PSA and negative biopsies
2. Patients treated either with a radical prostatectomy or