Current research projects
We are trying to apply a broad range of approaches to get an integrated view of the cellular and organismal response to DNA damage. We are using biochemistry, structural biology, cell biology and mouse genetics. In general, we are interested in dynamic chromosome transactions in the context of the nucleus.
Mechanisms of homologous recombination
Mechanism of homologous gene targeting
Mice and homologous recombination
Localized induction of DNA damage in cells
Interstrand DNA crosslink repair
