Publications
Müller, W. H., Essers, J., Humbel, B. M., and Verkleij, A. J. (1995). Enrichment of Penicillium chrysogenum microbodies by isopycnic centrifugation in nycodenz as visualized with immuno-electron microscopy. Biochim Biophys Acta 1245, 215-20.
Essers, J., de Stoppelaar, J. M., and Hoebee, B. (1995). A new rat repetitive DNA family shows preferential localization on chromosome 3, 12 and Y after fluorescence in situ hybridization and contains a subfamily which is Y chromosome specific. Cytogenet Cell Genet 69, 246-52.
Kanaar, R., Troelstra, C., Swagemakers, S. M. A., Essers, J., Smit, B., Franssen, J.-H., Pastink, A., Bezzubova, O., Buerstedde, J.-M., Clever, B., Heyer, W. D., and Hoeijmakers, J. H. J. (1996). Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation. Curr Biol 6: 828-38.
Essers, J., Hendriks, R. W., Swagemakers, S. M. A., Troelstra, C., de Wit, J., Bootsma, D., Hoeijmakers, J. H. J., and Kanaar, R. (1997). Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell 89: 195-204.
Jacobs, H., Fukita, Y., van der Horst, G. T. J., de Boer, J., Weeda, G., Essers, J., de Wind, N., Engelward, B. P., Samson, L., Verbeek, S., de Murcia, J. M., de Murcia, G., te Riele. H., and Rajewsky, K. (1998). Hypermutation of immunoglobulin genes in memory B cells of DNA repair- deficient mice. J Exp Med 187: 1735-43.
Swagemakers, S. M. A., Essers, J., de Wit, J., Hoeijmakers, J. H. J., and Kanaar, R. (1998). The human Rad54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase. J Biol Chem 273: 28292-97.
Tan, T. L. R#., Essers, J#., Citterio, E., de Wit, J., Swagemakers, S. M. A., de Wit, J., Benson, F.E., Hoeijmakers, J. H. J., and Kanaar, R. (1998). Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr Biol 9: 325-8 (#These authors contributed equally to this work).
Essers, J., van Steeg, H., Swagemakers, S.M.A., Vermeij, M., Hoeijmakers, J.H.J., and Kanaar, R. (2000). Homologous and non-homologous recombination differentially affect DNA damage repair in mice. EMBO J 19: 1703-10.
Niedernhofer L.J., Essers J., Weeda G., Beverloo B., de Wit J., Muijtjens M., Odijk H., Hoeijmakers J.H.J., Kanaar R. (2001)The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells. EMBO J. 22: 6540-9.
Kraakman-van der Zwet M, Overkamp W.J., van Lange R.E., Essers J., van Duijn-Goedhart A., Wiggers I., Swaminathan S.,van Buul P.P., Errami A., Tan R.T., Jaspers N.G., Sharan S.K., Kanaar R., Zdzienicka M.Z.. (2002) Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions. Mol Cell Biol. 2: 669-79.
Essers J., Houtsmuller A.B., van Veelen L., Paulusma C., Nigg A.L., Pastink A., Vermeulen W., Hoeijmakers J.H., Kanaar R. (2002) Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J. 8: 2030-7.
Essers J., Hendriks, R.W., Wesoly, J., Beerens, C.E.M.T., Smit, B., Hoeijmakers, J.H.J., Wyman, C., Dronkert, M.L.G., Kanaar, R. (2002) Analysis of mouse Rad54 expression and its implications for homologous recombination. DNA repair 1: 779-93.
Savouret C., Brisson E., Essers J., Kanaar R., Pastink A., te Riele H., Junien C., Gourdon G. (2003). CTG repeat instability and size variation timing in DNA repair-deficient mice. EMBO J. 22: 2264-73.
Abraham J., Lemmers B., Hande M.P., Moynahan M.E., Chahwan C., Ciccia A., Essers J., Hanada K., Chahwan R., Khaw A. K., McPherson P., Shehabeldin A., Laister R., Arrowsmith C., Kanaar R., West S. C., Jasin M., Hakem R. (2003). Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells. EMBO J. 22: 6137-47.
Aten, J. A., Stap, J., Krawczyk, P. M., van Oven, C. H., Hoebe, R. A., Essers, J., Kanaar, R. (2004). Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 303: 92-95.
Mills K. D., Ferguson D. O., Essers J., Eckersdorff M., Kanaar R., Alt F. W. (2004). Rad54 and DNA Ligase IV cooperate to maintain mammalian chromatid stability. Genes Dev. 18:1283-92.
Couedel C., Mills K.D., Marco B., Shen L., Olshen A., Johnson R.D., Nussenzweig A., Essers J., Kanaar R., Li G. C., Alt F. W., Jasin M. (2004) Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells. Genes Dev.11: 1293-304.
McPherson J. P., Lemmers B., Chahwan R., Pamidi A., Migon E., Matysiak-Zablocki E., Moynahan M.E., Essers J., Hanada K., Poonepalli A., Sanchez-Sweatman O., Khokha R., Kanaar R., Jasin M., Hande M. P., Hakem R. (2004). Involvement of mammalian Mus81 in genome integrity and tumor suppression Science 304:1822-6.
Budzowska M, Jaspers I, Essers J, de Waard H, van Drunen E, Hanada K, Beverloo B, Hendriks RW, de Klein A, Kanaar R, Hoeijmakers JH, Maas A. (2004) Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination. EMBO J. 23: 3548-58.
J. Essers, W.A. van Cappellen, A.F. Theil, E. van Drunen, N.G.J. Jaspers, J.H.J. Hoeijmakers, C. Wyman, W. Vermeulen and R. Kanaar (2005) Dynamics of relative chromosome position during the cell cycle. Mol Biol Cell 16: 769-75.
L.R. van Veelen, J. Essers, M.W.M.M. van de Rakt, C.C. Paulusma, R. Kanaar (2005) Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the rad51 paralogs, but not on rad52. Mutat Res 574: 34-49.
L. R. van Veelen, T. Cervelli, M.W.M.M. van de Rakt, A.F. Theil, J. Essers, R. Kanaar
(2005) Analysis of ionizing radiation-induced foci of DNA damage repair proteins. Mutat Res 574: 22-33.
F. A. de Vries, J. B. Zonneveld, A. van Duijn-Goedhart, M. Roodbergen, J. Boei, P. P. van Buul, J. Essers, H. van Steeg, A. A. van Zeeland, J. van Benthem, and A. Pastink. (2005) Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe. DNA Repair (Amst). 10:1121-8.
J. Essers#, A.F. Theil, C. Baldeyron, W.A. van Cappellen, A.B. Houtsmuller,R. Kanaar, W. Vermeulen. (2005) Nuclear dynamics of PCNA in DNA replication and repair Mol Cell Biol 21:9350-9.
(#Corresponding author)
J. Essers, A. B. Houtsmuller and R. Kanaar (2006) Analysis of DNA recombination and repair proteins in living cells by photobleaching microscopy, Methods Enzymol, 408:463-85.
J. Wesoly, S. Agarwal, S. Sigurdsson, W. Bussen, S. van Komen, J. Qin, H. van Steeg, J. van Benthem, E. Wassenaar, W.M. Baarends, M. Ghazvini, A. Tafel, H. Heath, N. Galjart, J. Essers, J. A. Grootegoed, N. Arnheim, O. Bezzubova, J. Buerstedde, P. Sung, and R. Kanaar. (2006) Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair and meiosis Mol Cell Biol, 26(3):976-89.
J. Essers, W. Vermeulen, A.B. Houtsmuller (2006) DNA damage repair; anytime, anywhere? Curr Opin Cell Biol. 18(3):240-6
S. Agarwal, R. Kanaar, and J. Essers (2006) The cell biology of homologous recombination. Topics in Current Genetics ed. edited by A. Aguilera and R. Rothstein. , Vol 17, 2007
Hanada K, Budzowska M, Modesti M, Maas A, Wyman C, Essers J, Kanaar R (2006) The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks. EMBO J. 25(20):4921-32.
L. Brugmans, R.Kanaar, J. Essers#. (2007) Analysis of DNA double strand break repair pathways in mice. Mutat Res, 614(1-2):95-108
K. Hanada, M. Vermeij, G.A. Garinis, M. C. de Waard, M. G. S. Kunen, L. Myers, A. Maas, D. J. Duncker, C. Meijers, H. C. Dietz, R. Kanaar and J. Essers. (2007) Perturbations of vascular homeostasis and aortic valve abnormalities in Fibulin-4 deficient mice. Circulation Research 100(5):738-46
E. S. Williams, J. Stap, J. Essers, B. Ponnaiya, M. S. Luijsterburg, P. M. Krawczyk, R. L. Ullrich, J. A. Aten, S. M. Bailey (2007) DNA double strand breaks are not sufficient to initiate the recruitment of TRF2. Nat. Gen. 39(6):696-698
V. van den Boom, S. M. Kooistra, M. Boesjes, K. Monzen, B. Geverts, A. B. Houtsmuller, J. Essers, L.s Drenth-Diephuis, B.J.L. Eggen. (2007) UTF1 is a chromatin-associated protein involved in ES cell differentiation. JCB 178(6):913-24
Dinant, C., de Jager, M., Essers, J., van Cappellen, W.A., Kanaar, R., Houtsmuller, A.B. and Vermeulen, W. (2007). Activation of multiple dna repair pathways by sub-nuclear damage induction methods. J. Cell Sci. 120, 2731-2740
Hanada, K., Budzowska, M., Davies, S.L., van Drunen, E., Beverloo, B.H., Maas, A., Essers, J., Hickson, I.D. and Kanaar, R. (2007). Involvement of the structure-specific endonuclease Mus81-Eme1 in double-strand DNA break-dependent replication restart. Nat. Struct. Mol. Biol. 14, 1096-1104.
Marchetti, F., Essers, J., Kanaar, R. and Wyrobek, A.J. (2007). Ionizing radiation-induced sperm DNA lesions are repaired in the egg by the NHEJ and HR pathways. Proc. Natl. Acad. Sci. USA 104, 17725-17729.
Stap, J., Krawczyk, P.M., van Oven, C.H., Barendsen, G., Essers, J., Kanaar, R. and Aten, J.A. (2008). Induction of linear tracks of DNA double-strand breaks by a-particle irradiation of cells. Nature Meth., in press.
J. Essers#, A.F. Theil, C. Baldeyron, W.A. van Cappellen, A.B. Houtsmuller,R. Kanaar, W. Vermeulen. (2005) Nuclear dynamics of PCNA in DNA replication and repair Mol Cell Biol 21:9350-9.
(#Corresponding author)
J. Essers, A. B. Houtsmuller and R. Kanaar (2006) Analysis of DNA recombination and repair proteins in living cells by photobleaching microscopy, Methods Enzymol, 408:463-85.
J. Essers, W. Vermeulen, A.B. Houtsmuller (2006) DNA damage repair; anytime, anywhere? Curr Opin Cell Biol. 18(3):240-6
S. Agarwal, R. Kanaar, and J. Essers (2006) The cell biology of homologous recombination. Topics in Current Genetics ed. edited by A. Aguilera and R. Rothstein. , Vol 17, 2007
L. Brugmans, R.Kanaar, J. Essers. (2007) Analysis of DNA double strand break repair pathways in mice. Mutat Res, 614(1-2):95-108
K. Hanada, M. Vermeij, G.A. Garinis, M. C. de Waard, M. G. S. Kunen, L. Myers, A. Maas, D. J. Duncker, C. Meijers, H. C. Dietz, R. Kanaar and J. Essers. (2007) Perturbations of vascular homeostasis and aortic valve abnormalities in Fibulin-4 deficient mice. Circulation Research 100(5):738-46
E. S. Williams, J. Stap, J. Essers, B. Ponnaiya, M. S. Luijsterburg, P. M. Krawczyk, R. L. Ullrich, J. A. Aten, S. M. Bailey (2007) DNA double strand breaks are not sufficient to initiate the recruitment of TRF2. Nat. Gen. 39(6):696-698
V. van den Boom, S. M. Kooistra, M. Boesjes, K. Monzen, B. Geverts, A. B. Houtsmuller, J. Essers, L.s Drenth-Diephuis, B.J.L. Eggen. (2007) UTF1 is a chromatin-associated protein involved in ES cell differentiation. JCB 178(6):913-24
